Be prepared to laugh your ass off the weekend of Sept. 15-18. The fourth annual Eugene Mirman Comedy Fest is back and ready to provide a slew of acts that will leave you in stitches. This year’s acts include Neil deGrasse Tyson, Kristen Schaal, Eugene Mirman, John Oliver, Jon Benjamin, Aisha Tyler and Matt Thompson, among many others. The four-day extravaganza that will be filling the both The Bell House and Union Hall is a 21+ event with tickets ranging from $10-20. For more information, visit eugenemirmanfestival.com.